Early Cancer Detection
identifying cancer earlier—when it’s most treatable
Early cancer detection focuses on identifying cancer signals at the earliest possible stages—often before symptoms appear.
While genetic testing helps determine who may be at higher risk, early cancer detection looks for biologic evidence of cancer activity through blood-based testing and targeted imaging.
How Early Detection Is Used
At CMoC, early cancer detection tools:
Complement standard screening (do not replace it)
Are selected based on individual risk profiles
Support proactive, precision-based surveillance
Blood-based testing can identify cancer signals across multiple tissue types, while imaging tools such as mammography, breast MRI, and low-dose lung CT support site-specific early detection.
Who May Benefit
Early cancer detection may be appropriate for patients with:
Elevated inherited or polygenic cancer risk
Personal or family cancer history
Desire for proactive surveillance beyond routine screening
Testing Options for Early Cancer Detection
Early cancer detection at CMoC combines advanced blood-based testing and targeted imaging to help identify cancer at its most treatable stages—often before symptoms develop. These tools are selected based on individual risk factors and are designed to complement standard screening, not replace it.
Blood-Based Early Cancer Detection
Blood-based testing analyzes circulating tumor DNA and other cancer-associated signals to identify the possible presence of cancer across multiple tissue types from a single blood draw. These tests can support proactive surveillance, particularly for patients with elevated inherited or polygenic risk or those seeking earlier insight beyond routine screening.
Certain blood-based options may also focus on specific cancer types, such as colorectal cancer, offering a noninvasive screening alternative for patients who are unable or unwilling to undergo traditional procedures.
Precision Cancer Imaging
Imaging remains a critical component of early cancer detection. Based on individual risk profiles, clinicians may recommend targeted imaging studies—such as mammography, breast MRI, or low-dose lung CT—to support early identification of site-specific cancers when outcomes are most favorable.
Choosing the Right Approach
Early cancer detection is not one-size-fits-all. Your clinician will help determine which combination of blood-based testing and imaging is appropriate based on your personal history, family history, genetic risk, and overall health goals—ensuring testing is purposeful, evidence-based, and clinically actionable.
Blood-Based Early Cancer Detection
Galleri by Grail - $945
Galleri is a multi-cancer early detection (MCED) blood test that analyzes circulating cell-free DNA (cfDNA) for tumor-specific methylation patterns across more than 55 cancer types.
It detects a “cancer signal” and can identify the tissue of origin, allowing cancers to be found earlier—often before symptoms or imaging changes occur.
Galleri is designed to complement, not replace, standard cancer screening and supports proactive, precision-based surveillance.
Shield by Gaurdant - $1495 or covered by Medicare
Shield is a blood-based colorectal cancer screening test that detects tumor-derived DNA alterations, including methylation and genomic changes associated with colorectal neoplasia.
It offers a non-invasive alternative for patients who decline or are unable to complete colonoscopy, with strong sensitivity for both early-stage cancers and advanced adenomas.
Early Cancer Detection Imaging
Mammogram
Breast MRI
Low Dose Lung CT
Take a Proactive Approach to Early Detection
Early cancer detection can provide valuable insight, especially for individuals at higher risk. Our clinicians will help you understand which testing options are appropriate and how they fit into your overall screening plan.